Genetic Recombination : Reviews and Protocols / edited by Alan S. Waldman.
Material type: TextLanguage: English Series: Methods in Molecular Biology ; 262 | Methods in molecular biology (Clifton, N.J.) ; v. 262.Publication details: Totowa, N.J. : Humana Press, c2004.Description: x, 260 p. : ill. (some col.) ; 24 cmISBN:- 1588292363 (alk. paper)
- 9781588292360
- 572.877 22 WAL
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General Books | CUTN Central Library Sciences | Non-fiction | 572.877 WAL (Browse shelf(Opens below)) | Available | 41052 |
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572.869 FUN Plasmid biology / | 572.869 FUN Plasmid biology / | 572.873 GU Structural bioinformatics / | 572.877 WAL Genetic Recombination : | 572.88 PAU MicroRNA : | 572.88 YAO MicroRNA protocols / | 572.886 GUO RNA nanotechnology and therapeutics : |
Part 1. Studying Recombination Events in Eukaryotes Part 2. Recombination as Reporter of genomic Instability Part 3. Recombination as a Tool for Producing Targeted Genetic Modification Part 4. Biochemistry of Recombination
Genetic recombination plays an essential role in such vitally important biological processes as DNA repair, regulation of gene expression, disease etiology, meiotic chromosome segregation, and evolution. In Genetic Recombination: Reviews and Protocols, prominent international investigators actively engaged in recombination research describe in great detail their best techniques for studying recombination. The methods range from approaches and model systems to be used in a variety of eukaryotic organisms and in a mammalian parasite, to biochemical analyses useful for furthering the understanding of recombination mechanisms. Additional techniques use recombination as a reporter of genomic instability in lower and higher eukaryotes and as a tool for producing targeted genetic modification. Each readily reproducible method includes step-by-step instructions, a background introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and highly practical, Genetic Recombination: Reviews and Protocols offers both novice and experienced investigators an illuminating synthesis of what we currently know about recombination, as well as a wide-ranging collection of powerful tools for elucidating its mechanisms and regulation throughout biology today.
Includes bibliographical references and index.
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