TY - BOOK AU - Shaw,Karen Joy[ed.] AU - Shaw,Karen Joy TI - Pathogen genomics: impact on human health T2 - Infectious disease SN - 1588290263 (alk. paper) U1 - 579.165 21 PY - 2002/// CY - Totowa, N.J. PB - Humana Press KW - Microbial genetics KW - Gene expression KW - Fungal gene expression KW - DNA microarrays KW - Pathogenic microorganisms KW - Genomics KW - Microbiologic Phenomena KW - genetics N1 - Includes bibliographical references and index; Leading infectious disease researchers and pharmaceutical scientists comprehensively review the latest genomic technologies and their application to the prevention, diagnosis, and treatment. The authors' cross-disciplinary approach, with expertise acquired from studying disease-causing viruses, bacteria, fungi, and protozoa, reveals how sequence information from diverse pathogens has uncovered novel targets for drug discovery, antigenic determinants for vaccine development, as well as diagnostic tools. The authors also discuss the application of DNA micoarrays and the impact of genome sequencing comparisons on the discovery and choices of novel drug targets. The result is a better understanding how genomic information can reveal the fundamentals of microbial pathogenesis and how organisms interact with their host environment.; Part1 Viruses Antivirual Drug Target Discoverry with DNA Microarrays; Chipping A way at HIV Pathogenesis; Microarray Analysis of Human Papillomavirus Pathogenesis; Ribozymes as Gene Therapeutic Agents for HIV/AIDS; Part II Bacteria ; Part III Fungi ; Part IV Protozoa UR - http://www.loc.gov/catdir/enhancements/fy0825/2002017200-d.html UR - http://www.loc.gov/catdir/enhancements/fy0825/2002017200-t.html ER -