TY  - BOOK
AU  - Jennison,Christopher
AU  - 
AU  - Turnbull,Bruce W.
TI  - Group sequential methods with applications to clinical trials
SN  - 0849303168 (alk. paper)
U1  - 615.190 21
PY  - 2000///
CY  - Boca Raton
PB  - Chapman & Hall/CRC
KW  - Clinical trials
KW  - Decision Theory
KW  - Statistics
KW  - Clinical Trials
KW  - Models, Statistical
KW  - Statistical methods
KW  - methods
N1  - Includes bibliographical references (p. [363]-386) and index; 
1. Introduction
2. Two-sided tests: Introduction
3. Two-sided tests: General applications
4. One-sided tests
5. Two-sided tests with early stopping under the null hypothesis
6. Equivalence tests
7. Flexible monitoring: The error spending approach
8. Analysis following a sequential test
9. Repeated confidence intervals
10. Stochastic curtailment
11. General group sequential distribution theory
12. Binary data
13. Survival data
14. Internal pilot studies: Sample size re-estimation
15. Multiple endpoints
16. Multi-armed trials
17. Adaptive treatment assignment
18. Bayesian approaches
19. Numerical computations for group sequential tests
N2  - Group Sequential Methods with Applications to Clinical Trials surveys and extends current methods for planning and conducting interim analyses. It describes group sequential stopping rules which can reduce average study length while controlling error probabilities. Procedures are presented in a manner which allows their easy implementation to the wide variety of data types arising from clinical trials." "Group Sequential Methods with Applications to Clinical Trials is an invaluable aid for medical statisticians in the pharmaceutical industry, medical research institutes and hospitals, as well as academic statisticians in biostatistics and epidemiology
UR  - http://www.loc.gov/catdir/enhancements/fy0646/99043218-d.html
ER  -