TY - BOOK AU - Frank,Steven A. AU - Frank,Steven A. TI - Microbial Life History: The Fundamental Forces of Biological Design SN - 9780691231181 PY - 2022///] CY - Princeton, NJ PB - Princeton University Press, KW - SCIENCE / Life Sciences / Biochemistry KW - bisacsh KW - SCIENCE / Life Sciences / Microbiology KW - SCIENCE / Life Sciences / Evolution KW - Prediction KW - Metabolism KW - Catabolism KW - Trade-off KW - Electron transport chain KW - Molecule KW - Glucose KW - Proteome KW - Oxidative stress KW - Enzyme KW - Protein KW - Glycolysis KW - Fitness (biology) KW - Escherichia coli KW - Reproductive value (population genetics) KW - Citric acid cycle KW - Genotype KW - Nicotinamide adenine dinucleotide KW - Kin selection KW - Weighting KW - Bacteria KW - Polymorphism (biology) KW - Mitochondrion KW - Redox KW - Reaction rate KW - Microorganism KW - Siderophore KW - Empirical research KW - Glycogen KW - Genetic correlation KW - Messenger RNA KW - Glucose uptake KW - Electrode KW - Quantity KW - Acetate KW - Competition KW - Processing (Chinese materia medica) KW - Phenotype KW - Combination KW - Michelangelo KW - Product inhibition KW - Wastewater treatment KW - Secretion KW - Schizosaccharomyces pombe KW - Starvation response KW - Electron acceptor KW - Symptom KW - Email KW - Microbial metabolism KW - Toxin KW - Thigh KW - Carbohydrate KW - Coefficient of relationship KW - Demography KW - Sibling KW - Natural selection KW - Oxidizing agent KW - Nutrient KW - Aerobic organism KW - Literature KW - Supper at Emmaus (Caravaggio) KW - Milan KW - Microbiological culture KW - Deficiency (medicine) KW - Genetic variability KW - Synthetic biology KW - Coefficient KW - Thomas Aquinas KW - Cell wall KW - Relative strength KW - Lipoprotein(a) KW - Supper at Emmaus (Caravaggio), Milan N1 - Frontmatter --; Contents --; Preface --; 1 Microbial Design --; Part 1 Theoretical Background --; 2 Forces of Design --; 3 Comparison and Causality --; 4 Brief Examples --; 5 Theory: Forces --; 6 Theory: Traits --; 7 Theory: Control --; 8 Studying Biological Design --; Part 2 The Design of Metabolism --; 9 Microbial Metabolism --; 10 Growth Rate --; 11 Thermodynamics: Biochemical Flux --; 12 Flux Modulation: Driving Force --; 13 Flux Modulation: Resistance --; 14 Variant Pathways --; 15 Tradeoffs --; 16 Predictions: Overflow Metabolism --; 17 Predictions: Diauxie, Electrons, Storage --; 18 Design Revisited --; References --; Index; restricted access N2 - A powerful framework for understanding how natural selection shapes adaptation and biological designDesign and diversity are the two great challenges in the study of life. Microbial Life History draws on the latest advances in microbiology to describe the fundamental forces of biological design and apply these evolutionary processes to a broad diversity of traits in microbial metabolism and biochemistry.Emphasizing how to formulate and test hypotheses of adaptation, Steven Frank provides a new foundation for exploring the evolutionary forces of design. He discusses the economic principles of marginal valuations, trade-offs, and payoffs in risky and random environments; the social aspects of conflict and cooperation; the demographic aspects of age and spatial heterogeneity; and the engineering control theory principles by which systems adjust to environments. Frank then applies these evolutionary principles to the biochemistry of microbial metabolism, providing the first comprehensive link between the forces that shape biological design and cellular energetics.Tracing how natural selection sculpts metabolism, Microbial Life History provides new perspectives on the life histories of organisms, from growth rate and survival to dispersal and defense against attack. Along the way, this incisive book addresses the conceptual and philosophical challenges confronting evolutionary biologists and other practitioners who study biological design and seek to apply its lessons UR - https://www.degruyterbrill.com/isbn/9780691231181 UR - https://www.degruyterbrill.com/document/cover/isbn/9780691231181/original ER -