03589cam a2200421Ka 4500 000q0204 WSP 20260416153406.0 cr cnu|||unuuu 200515s2020 si ob 001 0 eng WSPC eng WSPC 2019008599 9781786346858 (ebook) 1786346850 (ebook) 9781786346841 (hbk.) 1786346842 (hbk.) QP519.9.M64 R83 2020 TEC 059000 bisacsh TEC 015000 bisacsh SCI 049000 bisacsh 616.07/54 23 Rudin, M. (Markus), 1953- Molecular imaging : basic principles and applications in biomedical research / by Markus Rudin. 3rd ed. Singapore : World Scientific, [2020] 1 online resource (xxxi, 768 p.) Mode of access: World Wide Web. System requirements: Adobe Acrobat Reader. Includes bibliographical references and index. Foreword to the first edition -- Foreword of the second edition -- Foreword to the third edition -- About the author -- Acknowledgment -- Introduction -- Methodologies. Imaging techniques. Molecular reporter systems. Design of molecular imaging probes -- Applications. Drug imaging. Imaging gene expression. Imaging the function of gene products. Monitoring cell migration. Molecular imaging : translational aspects -- Appendices. Physical constants. Mathematical formulae. Natural amino acids. Nucleotides -- Index. "The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today. This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added"--Publisher's website. Molecular probes. Diagnostic imaging. Imaging systems in medicine. Electronic books. https://www.worldscientific.com/worldscibooks/10.1142/q0204#t=toc E-BOOK 49720 49720 0 0 ddc 0 0 CUTN CUTN 2026-04-16 0 616.07/54 EB04978 2026-04-16 15:48:00 https://doi.org/10.1142/q0204 2026-04-16 E-BOOK