03191nam a2200349 a 4500 00001300 WSP 20260416153417.0 m d cr bn||||||||| 110527s2011 si a sb 001 0 eng d 9789814313711 (electronic bk.) 981431370X 9789814313704 WSPC eng WSPC 547.2 22 Hart, David J. Organic synthesis via examination of selected natural products / David J. Hart. Singapore ; Hackensack, N.J. : World Scientific Pub. Co., c2011. x, 578 p. : ill. Includes bibliographical references and index. ch. 1. Introduction -- ch. 2. Steroids -- ch. 3. Prostaglandins -- ch. 4. Pyrrolizidine alkaloids -- ch. 5. Juvabione and the vicinal stereochemistry problem -- ch. 6. Functional group reactivity patterns and difunctional relationships -- ch. 7. Some unnatural products - Twistane and Triquinacene -- ch. 8. Alkaloids - Difunctional relationships and the importance of the Mannich reaction -- ch. 9. Alkaloids from "dart-poison" frogs -- ch. 10. Morphine and oxidative phenolic coupling -- ch. 11. Olefin synthesis and Cecropia juvenile hormone -- ch. 12. A recent example of structure determination through total synthesis and convergent syntheses : Lasonolide A -- ch. 13. Ionophores : Calcimycin -- ch. 14. Erythromycin A Aglycone. This book is written for advanced graduate and undergraduate students to expose them to a variety of strategies for the synthesis of organic compounds. This is done largely within the context of natural products synthesis, but some unnatural products synthesis is also included. Multiple approaches to each group of synthesis targets are presented, and the approaches are compared with one another with an eye on similarities and differences. General problems in organic synthesis (for example, strategies for the preparation of 6-membered rings and 5-membered rings, the importance of oxidation state, the problem of acyclic diastereoselectivity, the problem of controlling absolute stereochemistry, the importance of functional group relationships) are introduced early in the book and revisited throughout the text within the context of a variety of structurally unrelated natural products. The book provides readers with a somewhat historical overview of organic and natural products chemistry, and spans synthetic methodology that dates from the 1940's to the present time. It is written in a style that readers will find entertaining at times. It also contains lots of useful references with complete titles provided. Electronic reproduction. Singapore : World Scientific Publishing Co., 2011. System requirements: Adobe Acrobat Reader. Mode of access: World Wide Web. Available to subscribing institutions. Organic compounds Synthesis. Electronic books. World Scientific (Firm) 981431370X 9789814313704 http://www.worldscientific.com/worldscibooks/10.1142/7815#t=toc E-BOOK 49791 49791 0 0 ddc 0 0 CUTN CUTN 2026-04-16 0 547.2 EB04981 2026-04-16 15:50:00 https://doi.org/10.1142/7815 2026-04-16 E-BOOK