TY - BOOK AU - Zhao,Wenyi AU - TI - Handbook for chemical process research and development SN - 9781498767996 (hardcover : alk. paper) U1 - 615.19 23 PY - 2017///] ©2017 CY - Boca Raton : PB - CRC Press KW - Drugs KW - Pharmaceutical industry KW - Research KW - Methodology N1 - Includes bibliographical references and index; Chapter 1. Modes of reagent addition : control of impurity formation -- ; Chapter 2. Process optimization -- ; Chapter 3. Hazardous reactions -- ; Chapter 4. Catalytic reactions -- ; Chapter 5. Grignard reagent and related reactions -- ; Chapter 6. Challenging reaction intermediates -- ; Chapter 7. Protecting groups -- ; Chapter 8. Reaction solvents -- ; Chapter 9. Base reagent selection -- ; Chapter 10. Reagents for amide formation -- ; Chapter 11. Various reagent surrogates -- ; Chapter 12. Telescope approach -- ; Chapter 13. Stereochemistry -- ; Chapter 14. Design of new synthetic route -- ; Chapter 15. Reaction workup -- ; Chapter 16. Pharmaceutical salts -- ; Chapter 17. Solid form ER -