Neuroglia in the aging brain / edited by Jean de Vellis ; foreword by Paola S. Timiras.

Contributor(s):

De Vellis, Jean

Material type: Text

TextSeries: Contemporary neurosciencePublication details: Totowa, N.J. : Humana Press, c2002.Description: xiii, 513 p. : ill. ; 27 cmISBN:

0896035948 (alk. paper)

Subject(s):

DDC classification:

612.82 21 VEL

LOC classification:

QP363.2 .N483 2002

NLM classification:

WL 300

Online resources:

Contents:

Foreword by Paola Timiras ....................................................................................... v. Preface ........................................................................................................................ vii. Contributors ............................................................................................................. xiii. PART I. CELLULAR AND MOLECULAR CHANGES OF AGED AND REACTIVE ASTROCYTES. 1 •Neuromorphological Changes in Neuronal and Neuroglial Populations of the Cerebral Cortex in the Aging Rat: Neurochemical Correlations............................................................................. 3. Maria Angeles Peinado, Manuel Martinez, Maria Jesus Ramirez, Adoracion Quesada, Juan Angel Pedrosa, Concepcion Iribar, and Jose Maria Peinado 2 • Diversity in Reactive Astrocytes ................................................................... 17. Sudarshan K. Malhotra and Theodor K. Shnitka 3 • Astrocytic Reaction After Traumatic Brain Injury ..................................... 35. Jesús Boya, J. L. Calvo, Angel López-Carbonell, and José E. García-Mauriño PART II. NEURON–GLIA INTERCOMMUNICATION 4 • Astrocytes In Situ Exhibit Functional Neurotransmitter Receptors ....... 59. Marilee K. Shelton and Ken D. McCarthy 5 • Glia and Extracellular Space Diffusion Parameters in the Injured and Aging Brain ............................................ 77. Eva Syková 6 • Intercellular Diffusional Coupling between Glial Cells in Slices from the Striatum......................................................................................... 99. Brigitte Hamon, Jacques Glowinski, and Christian Giaume 7 • Glial Cell Involvement in Brain Repair and the Effects of Aging ......... 113. Elizabeth A. Howes and Peter J. S. Smith 8 • ATP Signaling in Schwann Cells ................................................................. 135. Thierry Amédée, Aurore Colomar, and Jonathan A. Coles PART III. NEUROTROPHINS, GROWTH FACTORS, AND NEUROHORMONES IN AGING AND REGENERATION 9 • Gliosis Growth Factors in the Adult and Aging Rat Brain ....................... 157. Gérard Labourdette and Françoise Eclancher 10 • Role of Fibroblast Growth Factor-2 in Astrogliosis ................................. 179. John F. Reilly 11 • Trophins as Mediators of Astrocyte Effects in the Aging and Regenerating Brain ............................................................................ 199. Judith Lackland and Cheryl F. Dreyfus ix x Contents 12 • Responses in the Basal Forebrain Cholinergic System to Aging ....... 217. Zezong Gu and J. Regino Perez-Polo 13 • Effects of Estrogens and Thyroid Hormone on Development and Aging of Astrocytes and Oligodendrocytes ................................. 245. Kevin Higashigawa, Alisa Seo, Nayan Sheth, Giorgios Tsianos, Hogan Shy, Latha Malaiyandi, and Paola S. Timiras PART IV. METABOLIC CHANGES 14 • Neurotoxic Injury and Astrocytes .............................................................. 259. Michael Aschner and Richard M. LoPachin 15 • Ammonium Ion Transport in Astrocytes: Functional Implications ........ 275. Neville Brookes PART V. ASTROCYTES AND THE BLOOD-BRAIN BARRIER IN AGING 16 • Molecular Anatomy of the Blood-Brain Barrier in Development and Aging...................................................................... 291. Dorothee Krause, Pedro M. Faustmann, and Rolf Dermietzel 17 • The Blood-Brain Barrier in the Aging Brain.............................................. 305. Gesa Rascher and Hartwig Wolburg 18 • Astrocytes and Barrier-provided Microvasculature in the Developing Brain ............................................................................ 321. Luisa Roncali PART VI. ASTROCYTES IN NEURODEGENERATIVE DISEASES 19 • Microglial and Astrocytic Reactions in Alzheimer's Disease ..................... 339. Douglas G. Walker and Thomas G. Beach 20 • Activated Neuroglia in Alzheimer's Disease ............................................ 365. Kurt R. Brunden and Robert C. A. Frederickson 21 • Reactive Astroglia in the Ataxic Form of Creutzfeldt-Jakob Disease: Cytology and Organization in the Cerebellar Cortex ..................................... 375. Miguel Lafarga, Nuria T. Villagra, and Maria T. Berciano 22 • Ischemic Injury, Astrocytes, and the Aging Brain ................................... 393. Robert Fern 23 • Glial-Neuronal Interactions during Oxidative Stress: Implications for Parkinson's Disease .......................................................... 407. Catherine Mytilineou 24 • Astrocytic Changes Associated with Epileptic Seizures ........................ 421. Angélique Bordey and Harald Sontheimer 25 • Synaptic and Neuroglial Pathobiology in Acute and Chronic Neurological Disorders............................................................................. 443. Lee J. Martin. 26 • Astrocytes and Ammonia in Hepatic Encephalopathy .......................... 477. Michael D. Norenberg. Index ........................................................................................................................ 497.

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Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
General Books	CUTN Central Library Medicine, Technology & Management	Non-fiction	612.82 VEL (Browse shelf(Opens below))	Available		42943

Includes bibliographical references and index.

Foreword by Paola Timiras ....................................................................................... v.
Preface ........................................................................................................................ vii.
Contributors ............................................................................................................. xiii.
PART I. CELLULAR AND MOLECULAR CHANGES OF AGED AND REACTIVE ASTROCYTES.
1 •Neuromorphological Changes in Neuronal
and Neuroglial Populations of the Cerebral Cortex in the Aging Rat:
Neurochemical Correlations............................................................................. 3.
Maria Angeles Peinado, Manuel Martinez, Maria Jesus Ramirez,
Adoracion Quesada, Juan Angel Pedrosa, Concepcion Iribar,
and Jose Maria Peinado

2 • Diversity in Reactive Astrocytes ................................................................... 17.
Sudarshan K. Malhotra and Theodor K. Shnitka

3 • Astrocytic Reaction After Traumatic Brain Injury ..................................... 35.
Jesús Boya, J. L. Calvo, Angel López-Carbonell,
and José E. García-Mauriño
PART II. NEURON–GLIA INTERCOMMUNICATION

4 • Astrocytes In Situ Exhibit Functional Neurotransmitter Receptors ....... 59.
Marilee K. Shelton and Ken D. McCarthy

5 • Glia and Extracellular Space Diffusion
Parameters in the Injured and Aging Brain ............................................ 77.
Eva Syková

6 • Intercellular Diffusional Coupling between Glial Cells in Slices
from the Striatum......................................................................................... 99.
Brigitte Hamon, Jacques Glowinski, and Christian Giaume

7 • Glial Cell Involvement in Brain Repair and the Effects of Aging ......... 113.
Elizabeth A. Howes and Peter J. S. Smith

8 • ATP Signaling in Schwann Cells ................................................................. 135.
Thierry Amédée, Aurore Colomar, and Jonathan A. Coles
PART III. NEUROTROPHINS, GROWTH FACTORS, AND NEUROHORMONES
IN AGING AND REGENERATION

9 • Gliosis Growth Factors in the Adult and Aging Rat Brain ....................... 157.
Gérard Labourdette and Françoise Eclancher

10 • Role of Fibroblast Growth Factor-2 in Astrogliosis ................................. 179.
John F. Reilly

11 • Trophins as Mediators of Astrocyte Effects in the Aging
and Regenerating Brain ............................................................................ 199.
Judith Lackland and Cheryl F. Dreyfus
ix
x Contents

12 • Responses in the Basal Forebrain Cholinergic System to Aging ....... 217.
Zezong Gu and J. Regino Perez-Polo

13 • Effects of Estrogens and Thyroid Hormone on Development
and Aging of Astrocytes and Oligodendrocytes ................................. 245.
Kevin Higashigawa, Alisa Seo, Nayan Sheth, Giorgios Tsianos,
Hogan Shy, Latha Malaiyandi, and Paola S. Timiras
PART IV. METABOLIC CHANGES

14 • Neurotoxic Injury and Astrocytes .............................................................. 259.
Michael Aschner and Richard M. LoPachin
15 • Ammonium Ion Transport in Astrocytes: Functional Implications ........ 275.
Neville Brookes
PART V. ASTROCYTES AND THE BLOOD-BRAIN BARRIER IN AGING
16 • Molecular Anatomy of the Blood-Brain Barrier
in Development and Aging...................................................................... 291.
Dorothee Krause, Pedro M. Faustmann, and Rolf Dermietzel
17 • The Blood-Brain Barrier in the Aging Brain.............................................. 305.
Gesa Rascher and Hartwig Wolburg
18 • Astrocytes and Barrier-provided Microvasculature
in the Developing Brain ............................................................................ 321.
Luisa Roncali
PART VI. ASTROCYTES IN NEURODEGENERATIVE DISEASES
19 • Microglial and Astrocytic Reactions in Alzheimer's Disease ..................... 339.
Douglas G. Walker and Thomas G. Beach
20 • Activated Neuroglia in Alzheimer's Disease ............................................ 365.
Kurt R. Brunden and Robert C. A. Frederickson
21 • Reactive Astroglia in the Ataxic Form of Creutzfeldt-Jakob Disease:
Cytology and Organization in the Cerebellar Cortex ..................................... 375.
Miguel Lafarga, Nuria T. Villagra, and Maria T. Berciano
22 • Ischemic Injury, Astrocytes, and the Aging Brain ................................... 393.
Robert Fern
23 • Glial-Neuronal Interactions during Oxidative Stress:
Implications for Parkinson's Disease .......................................................... 407.
Catherine Mytilineou
24 • Astrocytic Changes Associated with Epileptic Seizures ........................ 421.
Angélique Bordey and Harald Sontheimer
25 • Synaptic and Neuroglial Pathobiology in Acute and Chronic
Neurological Disorders............................................................................. 443.
Lee J. Martin.
26 • Astrocytes and Ammonia in Hepatic Encephalopathy .......................... 477.
Michael D. Norenberg.

Index ........................................................................................................................ 497.

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