000			03535cam a2200337 i 4500
001			18136768
003			CUTN
005			20170501153842.0
008			140502t20152015flua b 001 0 eng
010			_a 2014016454
020			_a9781466567610 (paperback : acidfree paper)
040			_beng _cCUTN
082	0	0	_a615.1 _223 _bCOO
084			_aMED071000 _aSCI013000 _2bisacsh
100	1		_aCooper, Raymond, _eauthor.
245	1	0	_aNatural products chemistry : _bsources, separations and structures / _cRaymond Cooper, George Nicola.
260			_aBoca Raton _bCRC Press _c2015
300			_axvii, 188 pages : _billustrations (some color) ; _c23 cm
504			_aIncludes bibliographical references and index.
520			_a"Compounds isolated from nature have long been known to possess biological profiles and pharmaceutical potential far greater than anything made by man. However, they are notoriously cumbersome to isolate and challenging to synthesize, and the path of natural products to viable drugs is an arduous journey. This book presents a practical guide to gathering, isolating, and discovering new pharmaceuticals from nature. It emphasizes the challenges and advantages of products acquired from nature over traditional compounds such as those arising from combinatorial chemistry"--
520			_a"This impressive natural products book is intended as an introduction for undergraduates to natural products for the first time, and for students studying pharmacognosy and related fields who wish to broaden their understanding of the field. The book is not meant to be comprehensive, but rather an introductory text to natural products chemistry, and hence is broad rather than in-depth. It covers the major classes of natural product compounds and their sources. It is a preparatory text for more advanced studies on synthesis, biosynthesis, and mode of action studies. The authors have selected examples from marine life, plants, insects, and, importantly, actual examples taken from the pharmaceutical industry (e.g., anti-infective compounds), which are not always discussed or worked on in universities. Natural products have played a central role in advancing synthetic and biosynthetic chemistry, medicine, and our understanding of nature. The training of chemists and pharmacognocists in the area of microscale chromatographic purification and spectroscopy is ever increasing to tackle the challenging questions in bioorganic chemistry and molecular biology. Over the lifetime of this author, dramatic changes have taken place in our approaches for the isolation, structure determination, and mode of action studies of chemicals from nature: from isolation of large quantities to even nanogram quantities. It continues to be essential to properly train natural products chemists in the area of the analytical challenges in the field of botanical medicines (supplements), and to provide confidence to encounter ever-increasing new challenges to solve critical biological questions at the interface of bioorganic and molecular biology"--
650		0	_aChromatographic analysis.
650		0	_aBiological products _xSeparation.
650		0	_aMicrobial metabolites _xSeparation.
650		7	_aMEDICAL / Pharmacology. _2bisacsh
650		7	_aSCIENCE / Chemistry / General. _2bisacsh
700	1		_aNicola, George _c(Chemist)
856	4	2	_3Cover image _uhttp://images.tandf.co.uk/common/jackets/websmall/978146656/9781466567610.jpg
906			_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg
942			_2ddc _cBOOKS
999			_c21669 _d21669