000			02586cam a22004214a 4500
003			CUTN
005			20181128152553.0
008			020123s2002 njua b 001 0 eng
020			_a1588290263 (alk. paper)
020			_a1588290263
041			_aEnglish
042			_apcc
060	1	0	_aQH 307.2 _bP297 2002
082	0	0	_a579.165 _221 _bSHA
100			_aShaw,Karen Joy[ed.]
245	0	0	_aPathogen genomics : _bimpact on human health / _cedited by Karen Joy Shaw.
260			_aTotowa, N.J. : _bHumana Press, _cc2002.
300			_axv, 309 p. : _bill. (some col.) ; _c27 cm.
505			_aLeading infectious disease researchers and pharmaceutical scientists comprehensively review the latest genomic technologies and their application to the prevention, diagnosis, and treatment. The authors' cross-disciplinary approach, with expertise acquired from studying disease-causing viruses, bacteria, fungi, and protozoa, reveals how sequence information from diverse pathogens has uncovered novel targets for drug discovery, antigenic determinants for vaccine development, as well as diagnostic tools. The authors also discuss the application of DNA micoarrays and the impact of genome sequencing comparisons on the discovery and choices of novel drug targets. The result is a better understanding how genomic information can reveal the fundamentals of microbial pathogenesis and how organisms interact with their host environment. _tPart1 Viruses Antivirual Drug Target Discoverry with DNA Microarrays _tChipping A way at HIV Pathogenesis _tMicroarray Analysis of Human Papillomavirus Pathogenesis _tRibozymes as Gene Therapeutic Agents for HIV/AIDS _tPart II Bacteria _tPart III Fungi _tPart IV Protozoa
650		0	_aMicrobial genetics.
650		0	_aGene expression.
650		0	_aFungal gene expression.
650		0	_aDNA microarrays.
650		0	_aPathogenic microorganisms.
650		0	_aGenomics.
650	1	2	_aMicrobiologic Phenomena
650	2	2	_aGenomics.
700	1		_aShaw, Karen Joy.
942			_2ddc _cBOOKS
490	1		_aInfectious disease
504			_aIncludes bibliographical references and index.
650	1	2	_xgenetics.
830		0	_aInfectious disease (Totowa, N.J.)
856	4	2	_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy0825/2002017200-d.html
856	4	1	_3Table of contents only _uhttp://www.loc.gov/catdir/enhancements/fy0825/2002017200-t.html
906			_a7 _bcbc _corignew _d1 _eocip _f20 _gy-gencatlg
999			_c26447 _d26447