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008 201123b ||||| |||| 00| 0 eng d
020 _a1588290603
020 _a9781588290601
041 _aEnglish
082 0 _a616.86
_222
_bMAL
100 _aMaldonado, Rafael.
245 0 0 _aMolecular Biology of Drug Addiction /
_cedited by Rafael Maldonado.
260 _aTotowa, N.J. :
_bHumana Press;
_cc2003.
300 _ax, 346 p. :
_bill. ;
_c26 cm.
505 _tPart I. Opioid Addiction
_tPart II. Psychostimulant Addiction
_tPart III. Cannabinoid Addiction
_tPart IV. Alcohol and Nicotine Addiction
520 _aRecent advances in molecular biotechnology have created powerful new models to clarify the neurobiological mechanisms involved in drug addiction. In Molecular Biology of Drug Addiction, leading authorities extensively survey these advances in a comprehensive multidisciplinary review of the most relevant molecular, genetic, and behavioral approaches used to investigate the neurobiological basis of drug addiction. In their exploration of the latest findings on opioid, psychostimulant, cannabinoid, alcohol, and nicotine addiction, the authors provide fresh insights into the genetic basis of drug addiction and the new therapeutic perspectives these have opened. They describe the technology available to generate conditional knockout mice and show how these mice can reveal the molecular basis of opioid, psychostimulant, and cannabinoid addiction. They also review the different behavioral models available to evaluate drug reward effects and analyze the genes involved in alcohol dependence. State-of-the-art and multidisciplinary, Molecular Biology of Drug Addiction offers neuro- and pharmaceutical scientists a clear understanding of a vast and complex literature, illuminating the decisive progress that has recently occurred and outlining the direction of future research on addictive processes.
650 0 _aDrug abuse
700 1 _aMaldonado, Rafael,
856 4 1 _uhttp://www.loc.gov/catdir/toc/fy033/2002024057.html
942 _2ddc
_cBOOKS
504 _aIncludes bibliographical references and index.
650 0 _xMolecular aspects.
700 1 _d1961-
856 4 1 _zTable of contents