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001			8983
003			CUTN
005			20160315133652.0
006			m d
007			cr cn|
008			110811s2011 njua sb 001 0 eng d
020			_a9780470921371 (electronic bk.)
020			_a0470921374 (electronic bk.)
020			_a9780470921364 (electronic bk.)
020			_a0470921366 (electronic bk.)
020			_z9780470386187
020			_z0470386185
020			_z9780470922972
020			_z0470922974
035			_a(OCoLC)746326254
037			_a10.1002/9780470921371 _bWiley InterScience
040			_aDG1 _beng _cDG1 _dCDX _dYDXCP _dN$T _dE7B _dOCLCQ
050		4	_aRS189.5.S65 _bC53 2011
072		7	_aMED _x023000 _2bisacsh
072		7	_aMED _x058170 _2bisacsh
072		7	_aMED _x071000 _2bisacsh
072		7	_aMED _x072000 _2bisacsh
082			_a615.1
090			_aRS189.5 _bSpe.Ch 2011
245	0	0	_aCharacterization of impurities and degradants using mass spectrometry _h[electronic resource] / _cedited by Birendra N. Pramanik, Mike S. Lee, Guodong Chen.
260			_aHoboken, N.J. : _bJohn Wiley, _cc2011.
300			_a1 online resource (1 online resource (xxii, 462 p.)) : _bill.
490	1		_aWiley series on pharmaceutical science and biotechnology.
504			_aIncludes bibliographical references and index.
505	0		_aFrontmatter -- Methodology. Introduction to Mass Spectrometry / Scott A Smith, Ruth Waddell Smith, Yu Xia, Zheng Ouyang -- LC Method Development and Strategies / Gang Xue, Yining Zhao -- Rapid Analysis of Drug-Related Substances Using Desorption Electrospray Ionization and Direct Analysis in Real Time Ionization Mass Spectrometry / Hao Chen, Jiwen Li -- Orbitrap High-Resolution Applications / Robert J Strife -- Structural Characterization of Impurities and Degradation Products in Pharmaceuticals Using High-Resolution LC-MS and Online Hydrogen/Deuterium Exchange Mass Spectrometry / Guodong Chen, Birendra N Pramanik -- Isotope Patten Recognition on Molecular Formula Determination for Structural Identification of Impurities / Ming Gu -- Application. Practical Application of Very High-Pressure Liquid Chromatography across the Pharmaceutical Developmentb6sManufacturing Continuum / Brent Kleintop, Qinggang Wang -- Impurity Identification for Drug Substances / David W Berberich, Tao Jiang, Joseph McClurg, Frank Moser, R Randy Wilhelm -- Impurity Identification in Process Chemistry by Mass Spectrometry / David Q Liu, Mingjiang Sun, Lianming Wu -- Structure Elucidation of Pharmaceutical Impurities and Degradants in Drug Formulation Development / Changkang Pan, Frances Liu, Michael Motto -- Investigation of Degradation Products and Extractables in Developing Topical OTC (Over the Counter) and NCE (New Chemical Entity) Consumer Healthcare Medication Products / Fa Zhang -- Characterization of Impurities and Degradants in Protein Therapeutics by Mass Spectrometry / Li Tao, Michael Ackerman, Wei Wu, Peiran Liu, Reb Russell -- Identification and Quantification of Degradants and Impurities in Antibodies / David M Hambly, Himanshu S Gadgil -- Index.
506			_aOnline version restricted to NUS staff and students only through NUSNET.
538			_aSystem requirements: Internet connectivity; World Wide Web browser.
538			_aMode of access: World Wide Web.
650		0	_aDrugs _xAnalysis.
650		0	_aDrugs _xSpectra.
650		0	_aMass spectrometry.
650		0	_aContamination (Technology)
650	1	2	_aMass Spectrometry _xmethods.
650	1	2	_aPharmaceutical Preparations _xanalysis.
650	2	2	_aDrug Contamination.
700	1		_aPramanik, Birendra N., _d1944- _zPRA
700	1		_aLee, Mike S., _d1960-
700	1		_aChen, Guodong.
710	2		_aWiley InterScience (Online service)
830		0	_aWiley series on pharmaceutical science and biotechnology.
942			_2ddc _cBOOKS
999			_c3627 _d3627