000 03589cam a2200421Ka 4500
001 000q0204
003 WSP
005 20260416153406.0
007 cr cnu|||unuuu
008 200515s2020 si ob 001 0 eng
040 _a WSPC
_b eng
_c WSPC
010 _z 2019008599
020 _a9781786346858
_q(ebook)
020 _a1786346850
_q(ebook)
020 _z9781786346841
_q(hbk.)
020 _z1786346842
_q(hbk.)
050 0 4 _aQP519.9.M64
_bR83 2020
072 7 _aTEC
_x059000
_2bisacsh
072 7 _aTEC
_x015000
_2bisacsh
072 7 _aSCI
_x049000
_2bisacsh
082 0 4 _a616.07/54
_223
100 1 _aRudin, M.
_q(Markus),
_d1953-
245 1 0 _aMolecular imaging :
_bbasic principles and applications in biomedical research /
_cby Markus Rudin.
250 _a3rd ed.
260 _aSingapore :
_bWorld Scientific,
_c[2020]
300 _a1 online resource (xxxi, 768 p.)
538 _aMode of access: World Wide Web.
538 _aSystem requirements: Adobe Acrobat Reader.
504 _aIncludes bibliographical references and index.
505 0 _aForeword to the first edition -- Foreword of the second edition -- Foreword to the third edition -- About the author -- Acknowledgment -- Introduction -- Methodologies. Imaging techniques. Molecular reporter systems. Design of molecular imaging probes -- Applications. Drug imaging. Imaging gene expression. Imaging the function of gene products. Monitoring cell migration. Molecular imaging : translational aspects -- Appendices. Physical constants. Mathematical formulae. Natural amino acids. Nucleotides -- Index.
520 _a"The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today. This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added"--Publisher's website.
650 0 _aMolecular probes.
650 0 _aDiagnostic imaging.
650 0 _aImaging systems in medicine.
655 0 _aElectronic books.
856 4 0 _uhttps://www.worldscientific.com/worldscibooks/10.1142/q0204#t=toc
942 _cE-BOOK
999 _c49720
_d49720