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005			20260416153408.0
007			cr cnu|||unuuu
008			200517s2020 si o 000 0 eng d
040			_a WSPC _b eng _c WSPC
020			_a9789811211874 _q(ebook)
020			_z9789811211867 _q(hbk.)
050	0	4	_aQP551 _b.P76 2020
072		7	_aSCI _x051000 _2bisacsh
072		7	_aSCI _x057000 _2bisacsh
072		7	_aSCI _x061000 _2bisacsh
082	0	4	_a572.6 _223
245	0	0	_aProtein interactions : _bcomputational methods, analysis and applications / _cedited by M Michael Gromiha.
260			_aSingapore : _bWorld Scientific, _c[2020]
300			_a1 online resource (xx, 403 p.)
538			_aMode of access: World Wide Web.
538			_aSystem requirements: Adobe Acrobat Reader.
520			_a"The interactions of proteins with other molecules are important in many cellular activities. Investigations have been carried out to understand the recognition mechanism, identify the binding sites, analyze the the binding affinity of complexes, and study the influence of mutations on diseases. Protein interactions are also crucial in structure-based drug design. This book covers computational analysis of protein-protein, protein-nucleic acid and protein-ligand interactions and their applications. It provides up-to-date information and the latest developments from experts in the field, using illustrations to explain the key concepts and applications. This volume can serve as a single source on comparative studies of proteins interacting with proteins/DNAs/RNAs/carbohydrates and small molecules"--Publisher's website.
505	0		_aProtein-protein interactions. Structural and dynamical aspects of evolutionarily conserved protein-protein complexes / Himani Tandon, Sneha Vishwanath and Narayanaswamy Srinivasan. A comprehensive overview of sequence-based protein-binding residue predictions for structured and disordered regions / Amita Barik and Lukasz Kurgan. Prediction of protein-protein complex structures by docking / Danial Pourjafar-Dehkordi and Martin Zacharias. Binding affinity of protein-protein complexes : experimental techniques, databases and computational methods / M Michael Gromiha. Mutational effects on protein-protein interactions / Jackson Weako, Attila Gursoy and Ozlem Keskin. Predicting the consequences of mutations / Hemant Kumar and Julia M Shifman -- Protein-nucleic acid interactions. Computational approaches for understanding the recognition mechanism of protein-nucleic acid complexes / Ambuj Srivastava, Dhanusha Yesudhas, A Kulandaisamy, Nisha Muralidharan, C Ramakrishnan, R Nagarajan and M Michael Gromiha. Prediction of nucleic acid binding proteins and their binding sites / Dhanusha Yesudhas, Ambuj Srivastava, Nisha Muralidharan, A Kulandaisamy, R Nagarajan and M Michael Gromiha. Predicting protein-binding sites in nucleic acids / Kyungsook Han. Docking algorithms and scoring functions / Arina Afanasyeva, Chioko Nagao and Kenji Mizuguchi. Recent progress of methodology development for protein-RNA docking / Yun Guo, Xiaoyong Pan and Hong-Bin Shen -- Protein-ligand interactions. Protein-carbohydrate complexes: binding site analysis, prediction, binding affinity and molecular dynamics simulations / K Veluraja, N R Siva Shanmugam, J Jino Blessy, R A Jeyaram, B Lalithamaheswari and M Michael Gromiha. Quantitative structure-activity relationship in ligand-based drug design : concepts and applications / Vishnupriya Kanakaveti, P Anoosha, R Sakthivel, S K Rayala and M Michael Gromiha. Protein-ligand interactions in molecular modeling and structure-based drug design / Devadasan Velmurugan, Dasararaju Gayathri, Chandrasekaran Ramakrishnan and Atanu Bhattacharjee. An overview of protein-ligand docking and scoring algorithms / Ruchika Bhat, Abhilash Jayaraj, Anjali Soni and B Jayaram.
650		0	_aProteins.
650		0	_aProteins _xResearch.
655		0	_aElectronic books.
700	1		_aGromiha, M. Michael.
856	4	0	_uhttps://www.worldscientific.com/worldscibooks/10.1142/11596#t=toc
942			_cE-BOOK
999			_c49734 _d49734