000			02705nam a2200397 a 4500
001			00013941
003			WSP
005			20260416153415.0
007			cr |nu|||unuuu
008			240707s2025 si o 000 0 eng d
010			_a 2024943385
020			_a9789811296536 _q(ebook)
020			_a9811296537 _q(ebook)
020			_z9789811296529 _q(hbk.)
040			_aWSPC _beng _cWSPC
050		4	_aQP551
072		7	_aSCI _x023000 _2bisacsh
072		7	_aSCI _x016000 _2bisacsh
082	0	4	_a572.636 _223
049			_aMAIN
100	1		_aBanerjee, Ipsita.
245	1	0	_aNotebook on structural biology techniques : _bstudy guide for practitioners / _cIpsita Banerjee ; editors, Rabin Banerjee, Jayati Sengupta.
260			_aSingapore : _bWorld Scientific, _cc2025.
300			_a1 online resource (vii, 243 p.)
505	0		_aX-ray crystallography -- Basics of electron and cryo-electron microscopy -- Single particle cryo-electron microscopy -- Small angle X-ray scattering -- Ribonucleotide reductases (RNRs) -- Solution structure of the dATP-inactivated class I ribonucleotide reductase from Leeuwenhoekiella blandensis by SAXS and cryo-electron microscopy -- Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding -- Mathematical supplement/appendix.
520			_a"This book describes the basic techniques required in learning structural biology. Apart from the classical and standard approaches like X-ray crystallography and SAXS (small angle X-ray scattering), it has quite an extensive chapter on the most recent approach; namely, cryo Electron Microscopy. The material is partly pedagogical, allowing readers to learn the subject, including some advanced topics. The application of these techniques to a specific example (Ribonucleotide Reductase) is discussed. At the end there is a detailed Mathematical Supplement, broken into six sections, that develop (from basic principles) the various mathematical machinery needed to learn the techniques of structural biology. It elaborates on the key mathematical concepts mentioned in the various chapters. Additionally, there is a collection of Ipsita's papers highlighting her seminal contributions, especially in the data processing of cryo EM"-- _cPublisher's website.
538			_aMode of access: World Wide Web.
538			_aSystem requirements: Adobe Acrobat Reader.
650		0	_aProteins _xAnalysis.
650		0	_aNucleic acids _xAnalysis.
655		0	_aElectronic books.
700	1		_aBanerjee, Rabin.
700	1		_aSengupta, Jayati.
856	4	0	_uhttps://www.worldscientific.com/worldscibooks/10.1142/13941#t=toc
942			_cE-BOOK
999			_c49778 _d49778