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008			110527s2011 si a sb 001 0 eng d
020			_a9789814313711 (electronic bk.)
020			_z981431370X
020			_z9789814313704
040			_aWSPC _beng _cWSPC
082	0	4	_a547.2 _222
100	1		_aHart, David J.
245	1	0	_aOrganic synthesis via examination of selected natural products / _cDavid J. Hart.
260			_aSingapore ; _aHackensack, N.J. : _bWorld Scientific Pub. Co., _cc2011.
300			_ax, 578 p. : _bill.
504			_aIncludes bibliographical references and index.
505	0		_ach. 1. Introduction -- ch. 2. Steroids -- ch. 3. Prostaglandins -- ch. 4. Pyrrolizidine alkaloids -- ch. 5. Juvabione and the vicinal stereochemistry problem -- ch. 6. Functional group reactivity patterns and difunctional relationships -- ch. 7. Some unnatural products - Twistane and Triquinacene -- ch. 8. Alkaloids - Difunctional relationships and the importance of the Mannich reaction -- ch. 9. Alkaloids from "dart-poison" frogs -- ch. 10. Morphine and oxidative phenolic coupling -- ch. 11. Olefin synthesis and Cecropia juvenile hormone -- ch. 12. A recent example of structure determination through total synthesis and convergent syntheses : Lasonolide A -- ch. 13. Ionophores : Calcimycin -- ch. 14. Erythromycin A Aglycone.
520			_aThis book is written for advanced graduate and undergraduate students to expose them to a variety of strategies for the synthesis of organic compounds. This is done largely within the context of natural products synthesis, but some unnatural products synthesis is also included. Multiple approaches to each group of synthesis targets are presented, and the approaches are compared with one another with an eye on similarities and differences. General problems in organic synthesis (for example, strategies for the preparation of 6-membered rings and 5-membered rings, the importance of oxidation state, the problem of acyclic diastereoselectivity, the problem of controlling absolute stereochemistry, the importance of functional group relationships) are introduced early in the book and revisited throughout the text within the context of a variety of structurally unrelated natural products. The book provides readers with a somewhat historical overview of organic and natural products chemistry, and spans synthetic methodology that dates from the 1940's to the present time. It is written in a style that readers will find entertaining at times. It also contains lots of useful references with complete titles provided.
533			_aElectronic reproduction. _bSingapore : _cWorld Scientific Publishing Co., _d2011. _nSystem requirements: Adobe Acrobat Reader. _nMode of access: World Wide Web. _nAvailable to subscribing institutions.
650		0	_aOrganic compounds _xSynthesis.
655		0	_aElectronic books.
710	2		_aWorld Scientific (Firm)
776	1		_z981431370X
776	1		_z9789814313704
856	4	0	_uhttp://www.worldscientific.com/worldscibooks/10.1142/7815#t=toc
942			_cE-BOOK
999			_c49791 _d49791