000 01837nam a22003018a 4500
001 1920
003 CUTN
005 20160316122621.0
008 000804s2000 nyu b 001 0 eng
010 _a00062399
020 _a0198503849 (hbk)
020 _a0198503830
040 _aDLC
_cDLC
_dOrLoB-B
042 _apcc
050 0 0 _aRS403
_b.C23 2000
082 _a615.19
090 _aRS403
_bCab
100 1 _aCabri, Walter.
_zCAB
245 1 0 _aFrom Bench to Market :
_bthe Evolution of Chemical Synthesis /
_cby Walter Cabri and Romano DiFabio.
260 _aNew York ;
_aSingapore :
_bOxford University Press,
_c2000.
300 _a266 p. :
_bill.
_c25 cm.
504 _aIncludes bibliographical references and index.
520 1 _a"The authors use the real chemical history of the development of drugs from several therapeutic areas as detailed case studies, each chosen to illustrate a range of issues and methodologies in industrial chemistry. Several chapters cover the development of the various [Beta]-lactam antibiotics; two chapters describe the discovery and synthesis of the anticancer drugs Idarubicin and Paclitaxal; in another chapter, the synthesis of the anti-viral drug Acyclovir and the 'patent war' that resulted are explored." "Between them, the authors represent considerable first-hand experience in pharmaceutical research and development. The technical, practical, and strategic information they have amassed make this essential reading for graduate and undergraduate chemists intending to work in the pharmaceutical industry, as well as for industrial chemists themselves. Lecturers teaching courses in medicinal and organic chemistry will also find it useful."--BOOK JACKET.
650 0 _aPharmaceutical chemistry.
650 0 _aDrug development.
700 1 _aDiFabio, Romano.
942 _2ddc
_cBOOKS
999 _c5272
_d5272