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020 _a9784431897569
020 _a4431897569 (Trade Cloth)
_cUSD 189.00 Retail Price (Publisher)
024 3 _a9784431897569
035 _a(WaSeSS)ssj0000476402
037 _a4431897569
_b00024965
040 _aBIP US
_dWaSeSS
_cLOC
100 1 _aNoda, Masaki
_eEditor
_4edt
_zNOD
210 1 0 _aMechanosensing Biology
245 1 0 _aMechanosensing Biology
_h[electronic resource]
260 _aNew York :
_bSpringer
_cFeb. 2011
506 _aLicense restrictions may limit access.
520 8 _aAnnotation
_bMechanical stress is vital to the functioning of the body, especially for tissues such as bone, muscle, heart, and vessels. It is well known that astronauts and bedridden patients suffer muscle and bone loss from lack of use. Even the heart, in pumping blood, causes mechanical stress to itself and to vascular tissue. With the loss of mechanical stress, homeostasis becomes impaired and leads to pathological conditions such as osteopenia, muscle atrophy, and vascular tissue dysfunction. In elderly populations, such mechanical pathophysiology, as well as the mechanical activities of locomotor and cardiovascular systems, is important because skeletal and heart functions decline and cause diseases in other organs. In this monograph, mechanical stress is discussed by experts in the field with respect to molecular, cellular, and tissue aspects in relation to medicine. Covering topics such as gravity and tissues and disuse osteoporosis, the book provides the most up-to-date information on cutting-edge advancements in the field of mechanobiology and is a timely contribution to research into locomotor and circulatory diseases that are major problems in contemporary society.
521 _aScholarly & Professional
_bSpringer
773 0 _tSpringerLink ebooks - Biomedical and Life Sciences (2011)
856 4 0 _uhttp://www.columbia.edu/cgi-bin/cul/resolve?clio8804130
_zFull text available from SpringerLink ebooks - Biomedical and Life Sciences (2011)
910 _aBowker Global Books in Print record
942 _2ddc
_cBOOKS
999 _c6397
_d6397