Chemical Logic’ discusses the common biochemical reaction types that underlie all metabolic reactions, helping students to connect organic chemistry with biochemistry, and ‘Chemical Logic Figures’ highlight the conversation of mechanisms and illustrate patterns that make learning pathways easier. (Provided for each of the central metabolic pathways.)
Strong on visualization including ‘Clear Art’ molecular structures created specifically for Lehninger to keep consistency with color and shape schemes, understandable figures which include numbers with annotated steps to explain complex processes, mechanism figures features step-by-step descriptions to help students understand the reaction process and summary figures to help students keep the big picture in mind while learning the specific.
This text has an emphasis on problem solving with in text ‘Worked Examples’ that take students through particular difficult equations to improve their quantitative problem-solving skills, and data ‘Analysis Problems’ that encourage students to synthesize what they have learned and apply their knowledge to the interpretation of data from the literature. More than 600 end-of-chapter problems (all available in Achieve) are also included to give students further opportunity to practice what they have learned.
Tools for understanding are provided including ‘Key Conventions’ and ‘Special Themes’ (Metabolic Integration, Obesity, and Diabetes, Evolution) as well as ‘Medical Insights and Applications-Icons’ used throughout the book denote material of special medical interest and updated to reflect the most current content.
‘Skills You Need’ activities support students with review and practice of prerequisite skills and concepts from chemistry, biology, and math for each biochemistry chapter.
Achieve is Macmillan Learning’s complete online learning system. It houses instructor resources to support teaching and a range of interactive resources and the full e-textbook to help students succeed in their course. Access to Achieve for instructors is available on this page. Student access to Achieve could be through their institution if the institution has signed a license or as a separate student purchase. The instructor must set up a course for students to benefit from this product.

This edition has been fully updated for focus, approachability, up-to-date content and to efficiently support student study. New and updated end-of-chapter questions are all available in the Achieve problem library with error-specific feedback and thorough solutions. These questions went through a rigorous development process to ensure they were robust, engaging and accurate.
All content has been streamlined so the text is focused on what is most important and useful to modern students and for future reference, and organized around principles for better understanding, providing a new learning path for students, through the emphasis on the fundamental principles of biochemistry.
This edition has also been streamlined for easier navigation. This is evident in the new, vibrant design which improves navigation through the content, and the carefully trimmed topics and subtopics to emphasize crucial content, resulting in shorter chapters and an overall reduction in book length, as based on extensive user feedback.

TABLE OF CONTENTS Preface viii
1. The Foundations of Biochemistry

I STRUCTURE AND CATALYSIS
2. Water, the Solvent of Life
3. Amino Acids, Peptides, and Proteins
4. The Three-Dimensional Structure of Proteins
5. Protein Function
6. Enzymes
7. Carbohydrates and Glycobiology
8. Nucleotides and Nucleic Acids
9. DNA-Based Information Technologies
10. Lipids
11. Biological Membranes and Transport
12. Biochemical Signaling

II BIOENERGETICS AND METABOLISM
13. Introduction to Metabolism
14. Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway
15. The Metabolism of Glycogen in Animals
16. The Citric Acid Cycle
17. Fatty Acid Catabolism
18. Amino Acid Oxidation and the Production of Urea
19. Oxidative Phosphorylation
20. Photosynthesis and Carbohydrate Synthesis in Plants
21. Lipid Biosynthesis
22. Biosynthesis of Amino Acids, Nucleotides, and Related Molecules
23. Hormonal Regulation and Integration of Mammalian Metabolism

III INFORMATION PATHWAYS
24. Genes and Chromosomes
25. DNA Metabolism
26. RNA Metabolism
27. Protein Metabolism
28. Regulation of Gene Expression Abbreviated Solutions to Problems
Glossary