Immunodominance :

Frelinger, Jeffrey A.

Immunodominance : the choice of the immune system / edited by Jeffrey A. Frelinger. - Weinheim : Wiley-VCH, c2006. - xxv, 288 p. : ill. (some col.) ; 25 cm.

Includes bibliographical references and index.

Mechanics of antigen processing. Class I MHC antigen processing The mechanics of class II processing: establichment of a peptide class II hierarchy The phenomenon of immunodomination: speculations on the nature of immunodominance Proteosome specificity and immuno-proteosomes. Endogenous antigen processing Effect of the T-cell repertoire on dominance. Regulation of early T-cell development in the thymus CD8 T-cell immunodominance, repertoire, and memory Effects of pathogens on the immune response. Listeria monocytogenes infection and the CD8' T-cell hierarchy Immunodominance in tuberculosis T-cell specificity and respiratory virus infections Effects of pathogens on the immune response The effects of pathogens on the immune system: viral hepatitis Immunodominance in the T-cell response to herpesviruses


This very first handbook on the topic summarizes the current concepts and brings together in one volume the critical arguments concerning the mechanisms relevant to immunodominance. In invited chapters written by the leaders in the field, the mechanisms whereby the immune system chooses the parts of a recognized pathogen in order to start the immune response are explained and the variety of biologic processes are Read more.

9783527312740 3527312749


Immune response
Immunoglobulins
Antigens
Antibody Formation
Antigen Presentation
Immune System--Regulation.--physiology.--physiology--physiology

571.9646 / FRE

QW 573 / I324 2006

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