Understanding cell signaling : motifs, recurring themes, and the theory of nonlinear dynamics /
Ferrell, James Ellsworth,
Understanding cell signaling : motifs, recurring themes, and the theory of nonlinear dynamics / James Ferrell. - FL : CRC Press, c2022. - pages cm
Includes bibliographical references and index.
Preface. Acknowledgements. 1. Introduction. 2. Receptors I: Monomeric Receptors and Ligands. 3. Receptors II: Multimeric Receptors and Cooperativity. 4. Downstream Signaling I: Stoichiometric Regulation. 5. Downstream Signaling II: Covalent Modification. 6. Downstream Signaling III: Regulated Production or Destruction. 7. Cascades and Amplification. 8. Bistability I: Systems with One-Time Dependent Variable. 9. Bistability II: Systems with Two Time-Dependent Variables. 10. Transcritical Bifurcations in Phase Separation and Infectious Disease. 11. Negative Feedback I: Stability and Speed. 12. Negative Feedback II: Adaption. 13. Adaption II: Incoherent Feed-Forward Regulation and State-Dependent Activation. 14. Negative Feedback 3: Oscillations. 15. Relaxation Oscillators. 16. Excitability. 17. Wrap-Up. Glossary. Index.
"All living cells continually detect and respond to external signals. This is true of prokaryotes, whether they are living alone or in biofilms, and it is even more manifestly true in multicellular eukaryotes, where communication between cells and coordination of the cells' behavior enables the organism to function as a unified whole. In large multicellular organisms like us humans, cells receive signals from their immediate neighbors through short-range signals like neurotransmitters and cell-surface molecules. They receive signals from more distant neighbors via longer-range diffusible molecules like morphogens, and from still-more distant neighbors by means of hormones that flow through the circulatory system. And they receive signals from the outside world via sense organs. Cells also monitor their own internal status, and there is a great deal of overlap between the cellular components involved in cell-cell communication and internal monitoring"--
9780367643836 9780815346036
2021007837
Cellular signal transduction.
QP517.C45 / F47 2021
571.74 / FER
Understanding cell signaling : motifs, recurring themes, and the theory of nonlinear dynamics / James Ferrell. - FL : CRC Press, c2022. - pages cm
Includes bibliographical references and index.
Preface. Acknowledgements. 1. Introduction. 2. Receptors I: Monomeric Receptors and Ligands. 3. Receptors II: Multimeric Receptors and Cooperativity. 4. Downstream Signaling I: Stoichiometric Regulation. 5. Downstream Signaling II: Covalent Modification. 6. Downstream Signaling III: Regulated Production or Destruction. 7. Cascades and Amplification. 8. Bistability I: Systems with One-Time Dependent Variable. 9. Bistability II: Systems with Two Time-Dependent Variables. 10. Transcritical Bifurcations in Phase Separation and Infectious Disease. 11. Negative Feedback I: Stability and Speed. 12. Negative Feedback II: Adaption. 13. Adaption II: Incoherent Feed-Forward Regulation and State-Dependent Activation. 14. Negative Feedback 3: Oscillations. 15. Relaxation Oscillators. 16. Excitability. 17. Wrap-Up. Glossary. Index.
"All living cells continually detect and respond to external signals. This is true of prokaryotes, whether they are living alone or in biofilms, and it is even more manifestly true in multicellular eukaryotes, where communication between cells and coordination of the cells' behavior enables the organism to function as a unified whole. In large multicellular organisms like us humans, cells receive signals from their immediate neighbors through short-range signals like neurotransmitters and cell-surface molecules. They receive signals from more distant neighbors via longer-range diffusible molecules like morphogens, and from still-more distant neighbors by means of hormones that flow through the circulatory system. And they receive signals from the outside world via sense organs. Cells also monitor their own internal status, and there is a great deal of overlap between the cellular components involved in cell-cell communication and internal monitoring"--
9780367643836 9780815346036
2021007837
Cellular signal transduction.
QP517.C45 / F47 2021
571.74 / FER