Essential bioinformatics /

Xiong, Jin

Essential bioinformatics / Jin Xiong - 1st ed. - New York : Cambridge University Press, 2006. - xi, 339 p.: ill., (some color) ; 27 cm.

1 Introduction to biological databases
2 Pairwise sequence alignment
3 Database similarity searching
4 Multiple sequence alignment
5 Profiles and hidden Markov models
6 Protein motifs and domain prediction
7 Gene prediction
8 Promoter and regulatory element prediction
9 Phylogenetics basics
10 Phylogenetic tree construction methods and programs
11 Protein structure basics
12 Protein structure visualization, comparision, and classification
13 Protein secondary structure prediction
14 Protein tertiary structure prediction
15 RNA structure prediction
16 Genome mapping, assembly, and comparison
17 Functional genomics
18 Proteomics

A concise yet comprehensive textbook of bioinformatics, which provides a broad introduction to the entire field. Written specifically for a life science audience, the basics of bioinformatics are explained, followed by discussions of the state-of-the-art computational tools available to solve biological research problems. All key areas of bioinformatics are covered including biological databases, sequence alignment, genes and promoter prediction, molecular phylogenetics, structural bioinformatics, genomics and proteomics. The book emphasizes how computational methods work and compares the strengths and weaknesses of different methods


9780521706100


Bioinformatics
Computational Biology

572.802 / XIO

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