MARC details
| 000 -LEADER |
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| fixed length control field |
03161nam a22003377a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
CUTN |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20231204120752.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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231204b |||||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781138034310 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781032091815 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781315270098 |
| 041 ## - LANGUAGE CODE |
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| Language |
English |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Edition number |
23 |
| Classification number |
615.1 |
| Item number |
RIT |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Ritz, Christian. |
| 240 ## - UNIFORM TITLE |
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| Uniform title |
<a href="Dose-Response Analysis Using R - Chapman & Hall/CRC the R Series">Dose-Response Analysis Using R - Chapman & Hall/CRC the R Series</a> |
| 245 ## - TITLE STATEMENT |
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| Title |
Dose-Response Analysis Using R - Chapman & Hall/CRC the R Series / |
| Statement of responsibility, etc |
Christian Ritz. |
| 250 ## - EDITION STATEMENT |
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| Edition statement |
1st ed. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Place of publication, distribution, etc |
Florida : |
| Name of publisher, distributor, etc |
CRC Press, |
| Date of publication, distribution, etc |
2020. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
xii, 213 p. : |
| Other physical details |
ill. ; |
| Dimensions |
22 cm. |
| 505 ## - FORMATTED CONTENTS NOTE |
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| Contents |
Continuous data<br/><br/>Binary and binomial dose-response data<br/><br/>Count dose-response data<br/><br/>Multinomial dose-response data<br/><br/>Time-to-event-response data<br/><br/>Benchmark dose estimation<br/><br/>Hierarchical nonlinear models<br/><br/>Appendix A: Estimation<br/><br/>Appendix B: Dose-response model functions<br/><br/>Appendix C: More R Code<br/><br/>Bibliography, Index |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
Nowadays the term dose-response is used in many different contexts and many different scientific disciplines including agriculture, biochemistry, chemistry, environmental sciences, genetics, pharmacology, plant sciences, toxicology, and zoology.<br/><br/>In the 1940 and 1950s, dose-response analysis was intimately linked to evaluation of toxicity in terms of binary responses, such as immobility and mortality, with a limited number of doses of a toxic compound being compared to a control group (dose 0). Later, dose-response analysis has been extended to other types of data and to more complex experimental designs. Moreover, estimation of model parameters has undergone a dramatic change, from struggling with cumbersome manual operations and transformations with pen and paper to rapid calculations on any laptop. Advances in statistical software have fueled this development.<br/><br/>Key Features:<br/><br/>Provides a practical and comprehensive overview of dose-response analysis.<br/>Includes numerous real data examples to illustrate the methodology.<br/>R code is integrated into the text to give guidance on applying the methods.<br/>Written with minimal mathematics to be suitable for practitioners.<br/>Includes code and datasets on the book's GitHub: https://github.com/DoseResponse.<br/>This book focuses on estimation and interpretation of entirely parametric nonlinear dose-response models using the powerful statistical environment R. Specifically, this book introduces dose-response analysis of continuous, binomial, count, multinomial, and event-time dose-response data. The statistical models used are partly special cases, partly extensions of nonlinear regression models, generalized linear and nonlinear regression models, and nonlinear mixed-effects models (for hierarchical dose-response data). Both simple and complex dose-response experiments will be analyzed. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
binomial dose-response data |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
pharmacology |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
chemistry |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
nonlinear models |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Time-to-event-response data |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Jensen, Signe Marie. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Gerhard, Daniel. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Streibig, Jens Carl. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Text Books |
