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Schaechter's mechanisms of microbial disease / [edited by] N. Cary Engleberg, Victor DiRita, Terence S. Dermody.

Contributor(s): Material type: TextTextPublication details: Philadelphia : Lippincott Williams & Wilkins, c2007.Edition: 4th edDescription: xxi, 762 p. : ill. (chiefly col.), col. maps ; 28 cmISBN:
  • 0781753422
  • 9780781753425
Uniform titles:
  • Mechanisms of microbial disease.
Subject(s): DDC classification:
  • 616.904 22 ENG
LOC classification:
  • QR46 .M463 2007
NLM classification:
  • QW 700
Online resources:
Contents:
Preface v Acknowledgments vii Contributors ix Figure Credits xv Part I: Principles 1 (138) Establishment of Infectious Diseases 3 (8) Normal Microbial Flora 11 (7) Biology of Infectious Agents 18 (21) Genetic Approaches to Studying Bacterial Pathogenesis 39 (17) Biological Basis for Antibacterial Action 56 (10) Innate Immunity 66 (24) Adaptive Immunity 90 (26) The Parasite's Way of Life 116 (10) Damage by Microbial Toxins 126 (13) Part II: Infectious Agents 139 (414) SECTION 1 BACTERIA Introduction to the Pathogenic Bacteria 141 (6) Staphylococci: Abscesses and Toxin-Mediated Diseases 147 (9) Streptococci and Enterococci: Sore Throats and Beyond 156 (8) Pneumococcus and Bacterial Pneumonia 164 (9) Neisseriae: Gonococcus and Meningococcus 173 (10) Bacteroides and Abscesses 183 (7) Enteric Bacteria: Secretory Diarrhea 190 (10) Invasive and Tissue-Damaging Enteric Bacterial Pathogens: Bloody Diarrhea and Dysentery 200 (15) Pseudomonas aeruginosa: A Ubiquitous Pathogen 215 (8) Bordetella pertussis and Whooping Cough 223 (7) Clostridia: Diarrheal Disease, Tissue Infection, Botulism, and Tetanus 230 (6) Legionella: Parasite of Amebas and Macrophages 236 (7) Helicobacter pylori: Pathogenesis of a ``Slow'' Bacterial Infection 243 (8) Mycobacteria: Tuberculosis and Leprosy 251 (12) Treponema pallidum and Syphilis: A Disease With a History 263 (8) Borrelia burgdorferi and Lyme Disease 271 (9) Cat Scratch Disease, Bacillary Angiomatosis, and Other Bartonelloses 280 (4) Chlamydiae: Genital, Ocular, and Respiratory Pathogens 284 (8) Rocky Mountain Spotted Fever and Other Rickettsioses 292 (8) Mycoplasma: Curiosity and Pathogen 300 (5) Strategies to Combat Bacterial Infections 305 (7) SECTION 2 VIRUSES Biology of Viruses 312 (18) Picornaviruses and Coronaviruses 330 (10) Arthropodborne Viruses 340 (7) Paramyxoviruses: Measles Virus and Respiratory Syncytial Virus 347 (10) Rabies 357 (6) Influenza and Its Viruses 363 (7) Rotaviruses, Noroviruses, and Other Viral Agents of Gastroenteritis 370 (6) Human Retroviruses: AIDS and Other Diseases 376 (13) Adenoviruses 389 (10) Human Papillomaviruses and Warts 399 (7) Alphaherpesviruses: Herpes Simplex Virus and Varicella-Zoster Virus 406 (9) Betaherpesviruses and Gammaherpesviruses: Cytomegalovirus and Epstein-Barr Virus 415 (9) Viral Hepatitis 424 (11) Antiviral Treatment Strategies 435 (10) Vaccines and Antisera for the Prevention and Treatment of Infectious Diseases 445 (6) SECTION 3 FUNGI Introduction to the Fungi and Mycoses 451 (4) Endemic Mycoses 455 (8) Opportunistic Fungal Infection 463 (9) Subcutaneous, Cutaneous, and Superficial Mycoses 472 (5) Antifungal Agents 477 (3) SECTION 4 PARASITES Introduction to Parasitology 480 (9) Blood and Tissue Protozoa 489 (15) Intestinal and Vaginal Protozoa 504 (9) Intestinal Helminths 513 (10) Tissue and Blood Helminths 523 (11) SECTION 5 MISCELLANEOUS PATHOGENS Prion Diseases 534 (7) Biological Agents of Warfare and Terrorism 541 (12) Part III: Pathophysiology of Infectious Diseases 553 (174) Diagnostic Principles 555 (11) Principles of Epidemiology 566 (6) Digestive System Infections 572 (16) Infections of the Central Nervous System 588 (15) Respiratory System Infections 603 (12) Urinary Tract Infections 615 (9) Infections of the Skin and Soft Tissue 624 (10) Infections of the Bones, Joints, and Muscles 634 (9) Sepsis 643 (7) Intravascular Infection 650 (9) Head and Neck Infections 659 (7) Sexually Transmitted Diseases 666 (7) Infections of the Immunocompromised Patient 673 (6) Acquired Immunodeficiency Syndrome 679 (12) Congenital and Perinatal Infections 691 (6) Zoonoses 697 (10) Fever: A Clinical Sign of Infection 707 (6) Health Care--Associated Infections 713 (6) Foodborne Diseases 719 (8) Index 727
Summary: Now in full color, the Fourth Edition of this text gives students a thorough understanding of microbial agents and the pathophysiology of microbial diseases. The text facilitates learning and recall by emphasizing unifying principles and paradigms, rather than forcing students to memorize isolated facts by rote. Case studies with problem-solving questions give students insight into clinical applications of microbiology. Each chapter ends with review and USMLE-style questions. For this edition, all schematic illustrations have been re-rendered in full color and new illustrations have been added. A new online site for students includes animations, USMLE-style questions, and all schematic illustrations and photographs from the text.
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Item type Current library Collection Call number Status Date due Barcode
General Books General Books CUTN Central Library Medicine, Technology & Management Non-fiction 616.904 ENG (Browse shelf(Opens below)) Available 43343

Rev. ed. of: Mechanisms of microbial disease / edited by Moselio Schaechter. 3rd ed. c1998.

Includes index.

Preface v
Acknowledgments vii
Contributors ix
Figure Credits
xv
Part I: Principles
1 (138)
Establishment of Infectious Diseases
3 (8)
Normal Microbial Flora
11 (7)
Biology of Infectious Agents
18 (21)
Genetic Approaches to Studying Bacterial Pathogenesis
39 (17)
Biological Basis for Antibacterial Action
56 (10)
Innate Immunity
66 (24)
Adaptive Immunity
90 (26)
The Parasite's Way of Life
116 (10)
Damage by Microbial Toxins
126 (13)
Part II: Infectious Agents
139 (414)
SECTION 1 BACTERIA
Introduction to the Pathogenic Bacteria
141 (6)
Staphylococci: Abscesses and Toxin-Mediated Diseases
147 (9)
Streptococci and Enterococci: Sore Throats and Beyond
156 (8)
Pneumococcus and Bacterial Pneumonia
164 (9)
Neisseriae: Gonococcus and Meningococcus
173 (10)
Bacteroides and Abscesses
183 (7)
Enteric Bacteria: Secretory Diarrhea
190 (10)
Invasive and Tissue-Damaging Enteric Bacterial Pathogens: Bloody Diarrhea and Dysentery
200 (15)
Pseudomonas aeruginosa: A Ubiquitous Pathogen
215 (8)
Bordetella pertussis and Whooping Cough
223 (7)
Clostridia: Diarrheal Disease, Tissue Infection, Botulism, and Tetanus
230 (6)
Legionella: Parasite of Amebas and Macrophages
236 (7)
Helicobacter pylori: Pathogenesis of a ``Slow'' Bacterial Infection
243 (8)
Mycobacteria: Tuberculosis and Leprosy
251 (12)
Treponema pallidum and Syphilis: A Disease With a History
263 (8)
Borrelia burgdorferi and Lyme Disease
271 (9)
Cat Scratch Disease, Bacillary Angiomatosis, and Other Bartonelloses
280 (4)
Chlamydiae: Genital, Ocular, and Respiratory Pathogens
284 (8)
Rocky Mountain Spotted Fever and Other Rickettsioses
292 (8)
Mycoplasma: Curiosity and Pathogen
300 (5)
Strategies to Combat Bacterial Infections
305 (7)
SECTION 2 VIRUSES
Biology of Viruses
312 (18)
Picornaviruses and Coronaviruses
330 (10)
Arthropodborne Viruses
340 (7)
Paramyxoviruses: Measles Virus and Respiratory Syncytial Virus
347 (10)
Rabies
357 (6)
Influenza and Its Viruses
363 (7)
Rotaviruses, Noroviruses, and Other Viral Agents of Gastroenteritis
370 (6)
Human Retroviruses: AIDS and Other Diseases
376 (13)
Adenoviruses
389 (10)
Human Papillomaviruses and Warts
399 (7)
Alphaherpesviruses: Herpes Simplex Virus and Varicella-Zoster Virus
406 (9)
Betaherpesviruses and Gammaherpesviruses: Cytomegalovirus and Epstein-Barr Virus
415 (9)
Viral Hepatitis
424 (11)
Antiviral Treatment Strategies
435 (10)
Vaccines and Antisera for the Prevention and Treatment of Infectious Diseases
445 (6)
SECTION 3 FUNGI
Introduction to the Fungi and Mycoses
451 (4)
Endemic Mycoses
455 (8)
Opportunistic Fungal Infection
463 (9)
Subcutaneous, Cutaneous, and Superficial Mycoses
472 (5)
Antifungal Agents
477 (3)
SECTION 4 PARASITES
Introduction to Parasitology
480 (9)
Blood and Tissue Protozoa
489 (15)
Intestinal and Vaginal Protozoa
504 (9)
Intestinal Helminths
513 (10)
Tissue and Blood Helminths
523 (11)
SECTION 5 MISCELLANEOUS PATHOGENS
Prion Diseases
534 (7)
Biological Agents of Warfare and Terrorism
541 (12)
Part III: Pathophysiology of Infectious Diseases
553 (174)
Diagnostic Principles
555 (11)
Principles of Epidemiology
566 (6)
Digestive System Infections
572 (16)
Infections of the Central Nervous System
588 (15)
Respiratory System Infections
603 (12)
Urinary Tract Infections
615 (9)
Infections of the Skin and Soft Tissue
624 (10)
Infections of the Bones, Joints, and Muscles
634 (9)
Sepsis
643 (7)
Intravascular Infection
650 (9)
Head and Neck Infections
659 (7)
Sexually Transmitted Diseases
666 (7)
Infections of the Immunocompromised Patient
673 (6)
Acquired Immunodeficiency Syndrome
679 (12)
Congenital and Perinatal Infections
691 (6)
Zoonoses
697 (10)
Fever: A Clinical Sign of Infection
707 (6)
Health Care--Associated Infections
713 (6)
Foodborne Diseases
719 (8)
Index 727

Now in full color, the Fourth Edition of this text gives students a thorough understanding of microbial agents and the pathophysiology of microbial diseases. The text facilitates learning and recall by emphasizing unifying principles and paradigms, rather than forcing students to memorize isolated facts by rote. Case studies with problem-solving questions give students insight into clinical applications of microbiology. Each chapter ends with review and USMLE-style questions. For this edition, all schematic illustrations have been re-rendered in full color and new illustrations have been added. A new online site for students includes animations, USMLE-style questions, and all schematic illustrations and photographs from the text.

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