Fundamentals of DNA Methylation / Dr. R.N. Shukla (Author)
Material type: TextLanguage: English Publication details: Jaipur : Oxford book company, 2022.Description: 256 p.: illISBN:- 9789391096502
- 616.042 SHU
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
---|---|---|---|---|---|---|
General Books | CUTN Central Library Medicine, Technology & Management | Non-fiction | 616.042 SHU (Browse shelf(Opens below)) | Available | 48261 |
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616.042 HYM Genetic epidemiology : | 616.042 POT Neurogenetics : | 616.042 SAH Genetic resource improvement in vegetable crops / | 616.042 SHU Fundamentals of DNA Methylation / | 616.0473 WIN Inflammation protocols / | 616.07 ARM Oxidants and Antioxidants : | 616.07 CRO Essentials of human disease / |
DNA usually exists as a double-stranded structure, with both strands coiled together to form the characteristic double-helix. Each single strand of DNA is a chain of four types of nucleotides having the bases: adenine, cytosine, guanine, and thymine. A nucleotide is a mono-, di-, or triphosphate deoxyribonucleoside; that is, a deoxyribose sugar is attached to one, two, or three phosphates. Chemical interaction of these nucleotides forms phosphodiester linkages, creating the phosphate-deoxyribose backbone of the DNA double helix with the bases pointing inward. Nucleotides are matched between strands through hydrogen bonds to formbase pairs. Adenine pairs with thymine, and cytosine pairs with guanine. DNA polymerases adds nucleotides to the 5' end of a strand of DNA. If a mismatch is accidentally incorporated, the polymerase is inhibited
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