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Netter's Essential Biochemistry /

By: Material type: TextLanguage: English Series: Netter Basic SciencePublication details: Elsevier Health Sciences, 2018.ISBN:
  • 0323388736
  • 9780323388733
Subject(s): DDC classification:
  • 572 RON
Online resources:
Contents:
Front Cover; Inside Front Cover; Marketing page; Netter's Essential Biochemistry; Copyright Page; Dedication; About the Author; Acknowledgments; Coauthors and Chapter Reviewers; About the Artist; Frank H. Netter, MD; Preface; Table Of Contents; 1 Human Karyotype and the Structure of DNA; Learning Objectives; Synopsis; 1. Chemical Structure of DNA; 2. Hydrogen Bonding Between Complementary Bases; 3. DNA Double Helix; 4. Packing of DNA Double Helices Into Chromatids; 5. Changes in DNA Topology; 6. Human Karyotype; Summary; Further Reading; Review Questions; 2 DNA Repair and Therapy of Cancer.
Learning ObjectivesSynopsis; 1. Base-Excision Repair; 2. Mismatch Repair; 3. Nucleotide-Excision Repair; 4. Repair of Double-Strand Breaks and Interstrand Crosslinks; 4.1. Nonhomologous End Joining; 4.2. Homologous Recombination Repair (Homology-Directed Repair); 5. DNA Damage Response Halts the Cell Cycle and Regulates Apoptosis; Summary; Further Reading; Review Questions; 3 DNA Replication; Learning Objectives; Synopsis; 1. DNA Replication; 2. Translesion Dna Synthesis; 3. Replication of the Ends of Chromosomes (Telomeres); Summary; Further Reading; Review Questions.
4 Clinical Tests Based on DNA or RNALearning Objectives; Synopsis; 1. Conventional Cytogenetics and Fluorescence in Situ Hybridization; 2. DNA Amplification by Polymerase Chain Reaction; 3. Electrophoresis and Melting Curve Analysis of DNA; 4. DNA Microarray-Based Technologies; 5. DNA Sequencing; 5.1. Sanger Sequencing; 5.2. Massive Parallel Sequencing; 6. Selected Clinical Applications of DNA-Based Testing; 6.1. Prenatal Diagnosis; 6.2. Other Common Nucleic Acid-Based Tests; Summary; Further Reading; Review Questions; 5 Basic Genetics for Biochemistry; Learning Objectives; Synopsis.
1. Chromosomes and Alleles2. Imprinting and Patterns of Inheritance; 3. Mutations and Markers; Summary; Review Question; 6 Transcription and RNA Processing; Learning Objectives; Synopsis; 1. DNA Methylation and Packing Impede Transcription; 2. The Process of Transcription; 3. Processing of RNA During and After Transcription; 3.1. Capping of Pre-mRNA; 3.2. Polyadenylation of Pre-mRNA; 3.3. Splicing of Pre-mRNA; 3.4. Alternative Splicing of Pre-mRNA; 3.5. Export of mRNA Into the Cytosol; 3.6. Degradation of mRNA; Summary; Further Reading; Review Questions.
7 Translation and Posttranslational Protein ProcessingLearning Objectives; Synopsis; 1. Codons and the Genetic Code; 2. Transfer RNAs; 3. Ribosomes Translate mRNA Into Protein; 4. Posttranslational Modification; 4.1. General Comments; 4.2. Glycosylation; 4.3. Acylation With Fatty Acids and Prenylation; 4.4. Phosphorylation, Sulfation, and Nitrosylation; 4.5. Ubiquitylation and SUMOylation; 5. Protein Sorting and Quality Control; Summary; Further Reading; Review Questions; 8 Cell Cycle and Cancer; Learning Objectives; Synopsis; 1. Cell Cycle and Its Regulation.
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Cover image Item type Current library Home library Collection Shelving location Call number Materials specified Vol info URL Copy number Status Notes Date due Barcode Item holds Item hold queue priority Course reserves
General Books CUTN Central Library Sciences Non-fiction 572 RON (Browse shelf(Opens below)) Available 54540

Front Cover; Inside Front Cover; Marketing page; Netter's Essential Biochemistry; Copyright Page; Dedication; About the Author; Acknowledgments; Coauthors and Chapter Reviewers; About the Artist; Frank H. Netter, MD; Preface; Table Of Contents; 1 Human Karyotype and the Structure of DNA; Learning Objectives; Synopsis; 1. Chemical Structure of DNA; 2. Hydrogen Bonding Between Complementary Bases; 3. DNA Double Helix; 4. Packing of DNA Double Helices Into Chromatids; 5. Changes in DNA Topology; 6. Human Karyotype; Summary; Further Reading; Review Questions; 2 DNA Repair and Therapy of Cancer.

Learning ObjectivesSynopsis; 1. Base-Excision Repair; 2. Mismatch Repair; 3. Nucleotide-Excision Repair; 4. Repair of Double-Strand Breaks and Interstrand Crosslinks; 4.1. Nonhomologous End Joining; 4.2. Homologous Recombination Repair (Homology-Directed Repair); 5. DNA Damage Response Halts the Cell Cycle and Regulates Apoptosis; Summary; Further Reading; Review Questions; 3 DNA Replication; Learning Objectives; Synopsis; 1. DNA Replication; 2. Translesion Dna Synthesis; 3. Replication of the Ends of Chromosomes (Telomeres); Summary; Further Reading; Review Questions.

4 Clinical Tests Based on DNA or RNALearning Objectives; Synopsis; 1. Conventional Cytogenetics and Fluorescence in Situ Hybridization; 2. DNA Amplification by Polymerase Chain Reaction; 3. Electrophoresis and Melting Curve Analysis of DNA; 4. DNA Microarray-Based Technologies; 5. DNA Sequencing; 5.1. Sanger Sequencing; 5.2. Massive Parallel Sequencing; 6. Selected Clinical Applications of DNA-Based Testing; 6.1. Prenatal Diagnosis; 6.2. Other Common Nucleic Acid-Based Tests; Summary; Further Reading; Review Questions; 5 Basic Genetics for Biochemistry; Learning Objectives; Synopsis.

1. Chromosomes and Alleles2. Imprinting and Patterns of Inheritance; 3. Mutations and Markers; Summary; Review Question; 6 Transcription and RNA Processing; Learning Objectives; Synopsis; 1. DNA Methylation and Packing Impede Transcription; 2. The Process of Transcription; 3. Processing of RNA During and After Transcription; 3.1. Capping of Pre-mRNA; 3.2. Polyadenylation of Pre-mRNA; 3.3. Splicing of Pre-mRNA; 3.4. Alternative Splicing of Pre-mRNA; 3.5. Export of mRNA Into the Cytosol; 3.6. Degradation of mRNA; Summary; Further Reading; Review Questions.

7 Translation and Posttranslational Protein ProcessingLearning Objectives; Synopsis; 1. Codons and the Genetic Code; 2. Transfer RNAs; 3. Ribosomes Translate mRNA Into Protein; 4. Posttranslational Modification; 4.1. General Comments; 4.2. Glycosylation; 4.3. Acylation With Fatty Acids and Prenylation; 4.4. Phosphorylation, Sulfation, and Nitrosylation; 4.5. Ubiquitylation and SUMOylation; 5. Protein Sorting and Quality Control; Summary; Further Reading; Review Questions; 8 Cell Cycle and Cancer; Learning Objectives; Synopsis; 1. Cell Cycle and Its Regulation.

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