Molecular genetic epidemiology : a laboratory perspective / Ian N.M. Day, ed.

By:

Day, Ian N. M

Contributor(s):

Day, Ian N. M

Material type: Text

TextLanguage: English Series: Principles and practicePublication details: Berlin ; New York : Springer, c2002.Description: xii, 214 p. : ill. (some col.) ; 24 cmISBN:

354041388X
3540413871
9783540413882

Subject(s):

DDC classification:

614.4 21 DAY

Online resources:

Contents:

1. Mapping Genes for Common Diseases: Statistical Planning, Power, Efficiency and Informatics 2. Human DNA Sampling and Banking 3. Microsatellite Genotyping 4. Minisatellite and Microsatellite DNA Fingerprinting 5. Multiplex Polymerase Chain Reaction and Immobilized Probes: Application to Cardiovascular Disease 6. The Special Case of HLA Genes: Detection and Resolution of Multiple Polymorphic Sites in a Single Gene 7. Microplate Array Diagonal Gel Electrophoresis (MADGE) Methodologies: The First Five Years 8. The Use of Sequence Analysis for Homozygote and Heterozygote Base Variation Discovery

Summary: This volume describes high-throughput approaches to a series of robust, established methodologies in molecular genetic studies of population samples. Such developments have been essential not only to linkage and association studies of single-gene and complex traits in humans, animals and plants, but also to the characterisation of clone banks, for example in mapping of genomes. Chapters have been written by developers or highly experienced end-users concerned with a diverse array of biological applications. The book should appeal to any researcher for whom costs and throughput in their genetics laboratory have become an issue

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Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
General Books	CUTN Central Library Medicine, Technology & Management	Non-fiction	614.4 DAY (Browse shelf(Opens below))	Available		43984

R.C.C
HB

1. Mapping Genes for Common Diseases: Statistical Planning, Power, Efficiency and Informatics 2. Human DNA Sampling and Banking 3. Microsatellite Genotyping 4. Minisatellite and Microsatellite DNA Fingerprinting 5. Multiplex Polymerase Chain Reaction and Immobilized Probes: Application to Cardiovascular Disease
6. The Special Case of HLA Genes: Detection and Resolution of Multiple Polymorphic Sites in a Single Gene 7. Microplate Array Diagonal Gel Electrophoresis (MADGE) Methodologies: The First Five Years 8. The Use of Sequence Analysis for Homozygote and Heterozygote Base Variation Discovery

This volume describes high-throughput approaches to a series of robust, established methodologies in molecular genetic studies of population samples. Such developments have been essential not only to linkage and association studies of single-gene and complex traits in humans, animals and plants, but also to the characterisation of clone banks, for example in mapping of genomes. Chapters have been written by developers or highly experienced end-users concerned with a diverse array of biological applications. The book should appeal to any researcher for whom costs and throughput in their genetics laboratory have become an issue

Includes bibliographical references and index.

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